Research Article

NLRP3 Inflammasome Simultaneously Involved in Autophagy and Phagocytosis of THP-1 Cells to Clear Aged Erythrocytes

Table 1

Results of THP-1 cells engulfed RBCs.

Phagocytosis rates of RBCs (100%)value
Untreated RBCs42°C-incubated RBCsIgG-opsonized RBCs123

Wild-type THP-1
shNC THP-1
ID3 THP-1
value
4NsNsNs
5
6

value, 1: untreated RBCs vs. 42°C-incubated RBCs; 2: untreated RBCs vs. IgG-opsonized RBCs; 3: 42°C-incubated RBCs vs. IgG-opsonized RBCs; 4: wild-type THP-1 vs. shNC THP-1; 5: Wild-type THP-1 vs. ID3 THP-1; and 6: shNC THP-1 vs. ID3 THP-1. , ns: not significant.