Associations between Circulating VEGFR2^hi-Neutrophils and Carotid Plaque Burden in Patients Aged 40-64 without Established Atherosclerotic Cardiovascular Disease

Table 1

Clinical and laboratory characteristics of patients.

Characteristics	Patients ()
Male, (%)/female, (%)	75 (51.7)/70 (48.3)
Age (years), Ме (LQ; UQ)	49.0 (44.0; 56.2)
BMI (kg/m^2), Ме (LQ; UQ)	26.9 (24.0; 30.4)
Obesity, (%)	37.0 (25.5)
Abdominal obesity, (%)	79 (54.5)
Smoking, (%)	28 (19.3)
T2DM, (%)	8 (5.51)
Hypertension, (%)	77 (53.1)
Dyslipidemia, (%)	129 (88.9)
Βeta-blockers, (%)	29 (20.0)
Renin-angiotensin system inhibitors, (%)	38 (26.2)
Diuretics, (%)	13 (8.96)
Statins, (%)	38 (26.2)
Leukocytes (), Ме (LQ; UQ)	5.75 (4.70; 6.90)
TC (mmol/l), Ме (LQ; UQ)	5.81 (5.03; 6.62)
LDL-C (mmol/l), Ме (LQ; UQ)	3.53 (3.00; 4.40)
HDL-C (mmol/l), Ме (LQ; UQ)	1.36 (1.19; 1.60)
TG (mmol/l), Ме (LQ; UQ)	1.30 (0.90; 1.78)
hsCRP (mg/l), Ме (LQ; UQ)	2.51 (1.25; 3.12)
VEGF (pg/ml), Ме (LQ; UQ)	309.4 (220.3; 401.6)
Glycated hemoglobin (%), Ме (LQ; UQ)	5.61 (5.16; 5.99)
eGFR (ml/min/1.73 m^2), Ме (LQ; UQ)	70.0 (61.0; 85.5)
cIMTm (mm), Ме (LQ; UQ)	0.645 (0.575; 0.710)
fIMTm (mm), Ме (LQ; UQ)	0.650 (0.550; 0.716)
Carotid plaque, (%)	98 (67.6)
Maximal carotid stenosis (%), Ме (LQ; UQ)	25.0 (0.00; 30.0)
cPTm (mm), Ме (LQ; UQ)	1.70 (1.40; 2.10)

BMI = body mass index; TC = total cholesterol; HDL-C = high-density lipoprotein cholesterol; LDL-C = low-density lipoprotein cholesterol; TG = triglycerides; eGFR = estimated glomerular filtration rate; hsCRP = high-sensitivity C-reactive protein; T2DM = type 2 diabetes mellitus; VEGF = vascular endothelial growth factor; cIMTm = mean carotid intima-media thickness; fIMTm = mean femoral intima-media thickness; cPTm = maximal carotid plaque thickness.