Macrophage Depletion Reduces Disease Pathology in Factor H-Dependent Immune Complex-Mediated Glomerulonephritis

Figure 6

Mϕs modulate cytokines in FH-dependent ICGN. The plasma and kidneys obtained at the time of sacrificed were stored at -80°C and processed as given in Materials and Methods. The concentrations of plasma TNFα (a), plasma IL-6 (b), and kidney M-CSF (c) were determined by ELISA. Results are representative of multiple experiments. , , and .

(a)

(b)

(c)