The Expression and Clinical Significance of PCNAP1 in Hepatocellular Carcinoma Patients

Table 2

ROC curve analysis of the use of plasma PCNAP1 for diagnosis and differential diagnosis of hepatocellular carcinoma.

Characteristics	AUC	SE		95% CI	Sensitivity	Specificity	Youden index
PCNAP1+AFP (HCC)	0.87	0.02	<0.001	0.82~0.92	78.74%	85.83%	0.65
PCNAP1 (HCC)	0.83	0.03	<0.001	0.78~0.88	70.08%	85.04%	0.55
AFP (HCC)	0.75	0.03	<0.001	0.69~0.82	66.93%	78.74%	0.46
PCNAP1 (colorectal cancer)	0.57	0.04	0.05	0.49~0.65	44.00%	69.29%	0.13
PCNAP1 (gastric cancer)	0.54	0.04	0.35	0.46~0.61	51.00%	60.43%	0.11