The NLRP3 Genetic Variant (rs10754555) Reduces the Risk of Adverse Outcome in Middle-Aged Patients with Chronic Coronary Syndrome

Table 6

Circulating levels of markers as related to NLRP3 genotypes in the total population.

Protein in serum	CC ()	CG ()	GG ()	value^1	value^2
IL-6 pg/mL	2.53 (1.66, 3.96)	2.49 (1.70, 3.83)	2.51 (1.64, 3.70)	0.932	0.712
Hs CRP mg/L	2.23 (1.08, 3.71)	2.28 (1.03, 4.22)	2.17 (0.97, 4.60)	0.823	0.547
IL-18 ng/mL	251 (198, 320)	246 (195, 315)	245 (188, 342)	0.854	0.832
IL-12 pg/mL	93 (59, 133)	86 (58, 132)	86 (62, 131)	0.610	0.353

¹ values represent the difference between genotypes (Kruskal-Wallis test). ² values represent the difference between homozygous wild type (CC) and the G-allele (CG and GG combined) (Mann–Whitney test).