Research Article
Identification of Malassezia globosa as a Gastric Fungus Associated with PD-L1 Expression and Overall Survival of Patients with Gastric Cancer
Table 2
The association of clinical characteristics with expression level of PD-L1.
| | Characteristics | Univariate analysis# | Multivariate analysis | | OR, 95% CI | value | OR, 95% CI | value |
| | Age (≥ 65 vs. < 65, years) | 1.763 (0.612-5.076) | 0.293 | — | | | Gender (male vs. female) | 2.058 (0.624-6.794) | 0.236 | — | | | BMI (≥ 24 vs. < 24, kg/m2) | 1.556 (0.501-4.831) | 0.445 | — | | | Tumor max size (≥ 4.6 vs. < 4.6, cm) | 2.187 (0.764-6.261) | 0.145 | — | | | Tumor location | | | | | | Upper | 1 (ref.) | | | | | Middle | 0.300 (0.061-1.467) | 0.137 | — | | | Lower | 0.521 (0.162-1.674) | 0.274 | — | | | Tumor differentiation (poor vs. high/moderate) | 1.014 (0.351-2.929) | 0.979 | — | | | Lauren classification | | | | | | Intestinal | 1 (ref.) | | | | | Diffuse | 0.807 (0.248-2.631) | 0.723 | — | | | Mix | 1.429 (0.264-7.737) | 0.679 | — | | | pTNM stage (IV vs. I/II/III) | 0.444 (0.107-1.846) | 0.264 | — | | | Lymphatic vessel invasive (positive vs. negative) | 2.632 (0.877-7.904) | 0.084 | 1.651 (0.469-5.806) | 0.435 | | Vascular invasive (positive vs. negative) | 3.100 (0.931-10.323) | 0.065 | 2.595 (0.662-10.168) | 0.171 | | Nerve invasive (positive vs. negative) | 0.976 (0.894-1.065) | 0.584 | — | | | HER2 status (3+ vs. 0/1+/2+) | 1.650 (0.371-7.344) | 0.511 | — | | | Malassezia globosa (high vs. low) | 3.626 (1.149-11.448) | 0.028 | 3.509 (1.056-11.656) | 0.040 |
|
|
#The variables with were included in multivariate analysis. was considered significant. OR: odds ratio; CI: confidence interval. |
