Significance of Immune-Related Genes in the Diagnosis and Classification of Intervertebral Disc Degeneration

Figure 7

(a) Consensus matrices of the 220 DEGs. (b) Differential expression histogram of the 11 IEGs in gene cluster A and B. (c) Differential immune cell infiltration among gene cluster A and B. (d) PCA for gene cluster A and B. (e) Differences in immune score between immune cluster A and B. (f) Differences in immune score between gene cluster A and B. (g) The Sankey diagram of relationship between immune patterns, gene patterns, and immune scores. (h) Differential expression levels of the ADAMTS, ATG7, MMP13, NLRP3, TGFB1, and TLR4 among immune cluster A and B. (i) Differential expression levels of the ADAMTS, ATG7, MMP13, NLRP3, TGFB1, and TLR4 among gene cluster A and B.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)