Polymorphisms in the ASAP1 and SP110 Genes and Its Association with the Susceptibility to Pulmonary Tuberculosis in a Mongolian Population
Table 3
The distribution of alleles of SNPs in the ASAP1 and SP110 genes in TB and healthy control population.
Gene
SNP
Alleles
TB, (%)
Control, (%)
Univariate logistic model
OR (95 CI)
value
ASAP1
rs10956514
G
225 (57.1)
241 (55.5)
1.0 (ref)
A
169 (42.9)
193 (44.5)
0.94 (0.71, 1.23)
0.648
rs4733781
C
226 (57.4)
240 (55.3)
1.0 (ref)
A
168 (42.6)
194 (44.7)
0.92 (0.7, 1.21)
0.551
rs2033059
T
226 (57.4)
240 (55.3)
1.0 (ref)
C
168 (42.6)
194 (44.7)
0.92 (0.7, 1.21)
0.551
rs12680942
G
228 (57.9)
240 (55.3)
1.0 (ref)
A
166 (42.1)
194 (44.7)
0.9 (0.68, 1.19)
0.457
rs1469288
A
226 (57.4)
239 (55.1)
1.0 (ref)
G
168 (42.6)
195 (44.9)
0.91 (0.69, 1.2)
0.507
rs17285138
A
228 (57.9)
240 (55.3)
1.0 (ref)
T
166 (42.1)
194 (44.7)
0.9 (0.68, 1.19)
0.457
SP110
rs1135791
A
329 (83.5)
371 (85.5)
1.0 (ref)
G
65 (16.5)
63 (14.5)
1.16 (0.8, 1.7)
0.431
rs9061
C
328 (83.2)
350 (80.6)
1.0 (ref)
T
66 (16.8)
84 (19.4)
0.84 (0.59, 1.2)
0.332
rs722555
C
228 (57.9)
283 (65.2)
1.0 (ref)
T
166 (42.1)
151 (34.8)
1.36 (1.03, 1.81)
0.030
rs3948464
G
394 (100)
430 (99.1)
1.0 (ref)
A
0 (0)
4 (0.9)
NA
NA
rs11679983
G
378 (95.9)
412 (94.9)
1.0 (ref)
A
16 (4.1)
22 (5.1)
0.79 (0.41, 1.53)
0.490
rs1365776
T
346 (87.8)
381 (87.8)
1.0 (ref)
C
48 (12.2)
53 (12.2)
1 (0.66, 1.51)
0.990
rs11556887
G
363 (92.1)
405 (93.3)
1.0 (ref)
A
31 (7.9)
29 (6.7)
1.19 (0.7, 2.02)
0.511
Data are presented as (%). SNP: single-nucleotide polymorphism; TB: tuberculosis; OR: odds ratio; CI: confidence intervals; NA: not applicable. values below 0.05 are highlighted in bold.
