Research Article
Polymorphisms in the ASAP1 and SP110 Genes and Its Association with the Susceptibility to Pulmonary Tuberculosis in a Mongolian Population
Table 5
The haplotypes analysis of ASAP1 and SP110 gene and TB in Mongolian population.
| Gene | SNPs | Group | Haplotype | TB case_F | Healthy control_F | OR | 95% CI | value |
| ASAP1 | rs1469288 rs10956514 rs12680942 rs2033059 rs4733781 rs17285138 | Active tuberculosis vs. heath controls | AGGTCA | 111 (0.563) | 119 (0.551) | 0.94 | 0.64-1.39 | 0.758 | GAACAT | 83 (0.419) | 97 (0.445) | 1.11 | 0.75-1.64 | 0.599 |
| SP110 | rs7222555 rs1135791 | Active tuberculosis vs. heath controls | CA | 113 (0.572) | 141 (0.649) | 1.38 | 0.93-2.05 | 0.112 | TA | 52 (0.263) | 45 (0.206) | 0.73 | 0.46-1.15 | 0.175 | TG | 31 (0.159) | 31 (0.142) | 0.89 | 0.52-1.53 | 0.680 | rs9061 rs11556887 | Active tuberculosis vs. heath controls | CG | 164 (0.832) | 175 (0.806) | 0.84 | 0.51-1.39 | 0.492 | TG | 17 (0.089) | 27 (0.127) | 1.50 | 0.79-2.85 | 0.211 | TA | 16 (0.079) | 15 (0.067) | 0.84 | 0.40-1.75 | 0.641 |
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Note: SNP: single-nucleotide polymorphism; TB: tuberculosis; OR: odds ratio; CI: confidence intervals; vs., versus.
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