Research Article

Polymorphisms in the ASAP1 and SP110 Genes and Its Association with the Susceptibility to Pulmonary Tuberculosis in a Mongolian Population

Table 5

The haplotypes analysis of ASAP1 and SP110 gene and TB in Mongolian population.

GeneSNPsGroupHaplotypeTB case_FHealthy control_FOR95% CI value

ASAP1rs1469288
rs10956514
rs12680942
rs2033059
rs4733781
rs17285138
Active tuberculosis vs. heath controlsAGGTCA111 (0.563)119 (0.551)0.940.64-1.390.758
GAACAT83 (0.419)97 (0.445)1.110.75-1.640.599

SP110rs7222555
rs1135791
Active tuberculosis vs. heath controlsCA113 (0.572)141 (0.649)1.380.93-2.050.112
TA52 (0.263)45 (0.206)0.730.46-1.150.175
TG31 (0.159)31 (0.142)0.890.52-1.530.680
rs9061
rs11556887
Active tuberculosis vs. heath controlsCG164 (0.832)175 (0.806)0.840.51-1.390.492
TG17 (0.089)27 (0.127)1.500.79-2.850.211
TA16 (0.079)15 (0.067)0.840.40-1.750.641

Note: SNP: single-nucleotide polymorphism; TB: tuberculosis; OR: odds ratio; CI: confidence intervals; vs., versus.