Peptidoglycan-Like Components in Z-100, Extracted from Mycobacterium tuberculosis Strain Aoyama B, Increase IL-12p40 via NOD2

Table 1

Concentration of amino acids, amino sugars, and neutral sugars in Z-100 and nonanion and anion fractions.

	Concentration (nmol/mL)
	Z-100	Nonanion	Anion
Aspartic acid	49.42	2.36	10.22
Threonine	51.91	7.68	10.13
Serine	32.98	3.53	6.32
Glutamic acid	88.86	8.06	29.58
Glycine	112.13	6.01	17.27
Alanine	122.91	12.94	39.34
Valine	37.04	3.03	7.76
Methionine	0.71	0.19	0.59
Isoleucine	13.85	0.93	3.02
Leucine	21.02	1.08	4.43
Tyrosine	6.55	0.42	1.95
Phenylalanine	4.19	0.18	0.69
Lysine	14.60	1.44	2.72
Histidine	8.05	0.28	2.23
Arginine	12.40	0.88	3.51
Proline	39.05	5.97	8.02
Diaminopimelic acid	38.33	5.39	18.33
Glucosamine	33.80	7.79	11.49
Galactosamine	18.22	13.44	<2.33
Muramic acid	10.69	1.22	7.09
Arabinose	2951.44	2304.34	101.25
Mannose	6014.23	4843.58	56.06
Glucose	1277.78	725.20	12.77
Galactose	364.02	237.57	37.19