Machine Learning-Devised Immune-Related lncRNA Signature Panel Predicts the Prognosis and Immune Landscape in Breast Cancer Novel IRLP Signature in BRCA

Figure 6

Evaluations of TIICs and immunosuppression-related genes by the IRLP signature. CIBERSORT showed that the high-risk group was positively associated with a higher infiltration level of macrophages M2/M0 and negatively associated with CD8⁺ T cells in all subtypes including luminal A (a), luminal B (b), TNBC (c), and HER2 (d). High-risk group was positively correlated with higher expression levels of LAG3 (e), CTLA4 (f), PDCD1 (g), and PDCD1LG2 (h).

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