Polymorphisms of ATG5 Gene Are Associated with Autoimmune Thyroid Diseases, Especially Thyroid Eye Disease

Table 4

Comparisons of genotype frequencies in AITD patients and controls.

SNP ID		Allele/genotype frequency (%)				value [OR (95% CI)]
		Control	AITD	GD	HT	AITDs vs. C	GD vs. C	HT vs. C
rs6568431	AA	67 (8.7)	88 (10.7)	59 (10.7)	29 (10.7)	0.200 [1.244 (0.890-1.737)]	0.247 [1.242 (0.860-1.796)]	0.346 [1.247 (0.787-1.974)]
	AC+CC	697 (91.3)	736 (89.3)	494 (89.3)	242 (89.3)	Reference	Reference	Reference
rs548234	CC	53 (6.9)	65 (7.9)	43 (7.8)	21 (7.7)	0.474 [1.147 (0.787-1.673)]	0.563[1.131 (0.745-1.718)]	0.656 [1.127 (0.666-1.906)]
	CT+TT	711 (93.1)	760 (92.1)	510 (92.2)	250 (92.3)	Reference	Reference	Reference
rs6937876	GG	70 (9.2)	89 (10.8)	61 (11.0)	28 (10.3)	0.277 [1.201 (0.863-1.670)]	0.263 [1.229 (0.856-1.766)]	0.572 [1.142 (0.720-1.813)]
	AG+AA	694 (90.8)	735 (89.2)	492 (89.0)	243 (89.7)	Reference	Reference	Reference