The Frequency of Intrathyroidal Follicular Helper T Cells Varies with the Progression of Graves’ Disease and Hashimoto’s Thyroiditis

Figure 2

The frequencies of CD4⁺CXCR5⁺, CD4⁺CXCR5⁺PD-1⁺, and CD4⁺CXCR5⁺ICOS^high Tfh cells in the thyroid of GD and HT patients. (a) Representative dot plot showing the gating strategy for Tfh cells gated on CD4⁺ T cells. (b–d) The frequencies of CD4⁺CXCR5⁺, CD4⁺CXCR5⁺PD-1⁺, and CD4⁺CXCR5⁺ICOS^high Tfh cells in patients with GD (), HT (), and nAITD ().

(a)

(b)

(c)

(d)