Human Neutrophil Antigen Genotype and Allele Frequencies in Iranian Blood Donors
Table 4
The distribution of HNA genotype frequencies. HNA genotype frequency distribution in the Iranian population tested for the deviation of Hardy–Weinberg equilibrium.
Genotype frequency
Observed
Expected
Hardy–Weinberg analysis
Number
%
Number
%
value
HNA1aa
21
14
16.7
11.3
861
0.125
HNA1bb
65
43
59.9
40.2
HNA1ab
55
37
63.4
42.6
HNA1ac
3
2
3.02
2.00
HNA1bc
4
3
5.70
3.8
HNA1cc
1
1
0.13
0.1
HNA3aa
58
38.7
57.7
38.5
0.448
0.799
HNA3bb
19
12.7
21.8
14.5
HNA3ab
73
48.6
70.5
47
HNA4aa
110
73.3
108
72
0.601
0.740
HNA4bb
4
2.7
3
2
HNA4ab
36
24
39
26
HNA5aa
77
51.3
78.2
52
0.179
0.915
HNA5bb
12
8
10.7
7
HNA5ab
61
40.7
61.1
41
HNAs: human neutrophil antigens; : chi-squared test value. No significant deviation from Hardy–Weinberg equilibrium was observed ().
