Insights from Dysregulated mRNA Expression Profile of β-Cells in Response to Proinflammatory Cytokines

Figure 1

Changed expression pattern of mRNAs in cytokine-mediated pancreatic β-cell destruction. (a) The heat map of differentially expressed mRNAs in pancreatic β-cells treated with a mix of cytokines, including IL-1β, TNF-α, and IFN-γ, compared with control cells from RNA sequencing data. (b) Volcano analysis showing differentially expressed mRNAs in cytokine-treated pancreatic β-cells and control cells.

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