Research Article
Insights from Dysregulated mRNA Expression Profile of β-Cells in Response to Proinflammatory Cytokines
Table 1
The top 20 upregulated and downregulated mRNAs.
| Upregulated mRNA | log2 (fold change) | Downregulated mRNA | log2 (fold change) |
| Gbp2 | 8.454 | Cox6a2 | -2.422 | Cd74 | 8.091 | Gm13889 | -2.395 | Ifitm3 | 8.008 | Slc16a3 | -2.208 | Ifi47 | 7.497 | Hist1h1c | -2.106 | Gbp6 | 7.391 | Lcp2 | -2.091 | Iigp1 | 7.332 | Ccnb2 | -2.062 | Serping1 | 7.246 | Mki67 | -2.055 | Ifit3 | 7.166 | Nptx1 | -2.039 | Gbp10 | 7.142 | Cdkn3 | -1.983 | Cxcl10 | 7.11 | Slc39a8 | -1.923 | Zbp1 | 7.019 | Hist1h2bc | -1.901 | Gbp3 | 7.015 | Pif1 | -1.847 | Cxcl9 | 6.948 | Nrcam | -1.824 | Gbp4 | 6.94 | Cenpf | -1.823 | Tgtp2 | 6.905 | Hist1h2bg | -1.818 | Ccl2 | 6.854 | Ckb | -1.817 | Tgtp1 | 6.822 | Troap | -1.804 | Gm43302 | 6.654 | Nek2 | -1.799 | Neurl3 | 6.615 | Fam64a | -1.795 | Apol9b | 6.586 | Slc7a2 | -1.791 |
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