Research Article

Insights from Dysregulated mRNA Expression Profile of β-Cells in Response to Proinflammatory Cytokines

Table 1

The top 20 upregulated and downregulated mRNAs.

Upregulated mRNAlog2 (fold change)Downregulated mRNAlog2 (fold change)

Gbp28.454Cox6a2-2.422
Cd748.091Gm13889-2.395
Ifitm38.008Slc16a3-2.208
Ifi477.497Hist1h1c-2.106
Gbp67.391Lcp2-2.091
Iigp17.332Ccnb2-2.062
Serping17.246Mki67-2.055
Ifit37.166Nptx1-2.039
Gbp107.142Cdkn3-1.983
Cxcl107.11Slc39a8-1.923
Zbp17.019Hist1h2bc-1.901
Gbp37.015Pif1-1.847
Cxcl96.948Nrcam-1.824
Gbp46.94Cenpf-1.823
Tgtp26.905Hist1h2bg-1.818
Ccl26.854Ckb-1.817
Tgtp16.822Troap-1.804
Gm433026.654Nek2-1.799
Neurl36.615Fam64a-1.795
Apol9b6.586Slc7a2-1.791