Research Article
Predictors of Response to Oral Medications and Low-Histamine Diet in Patients with Chronic Urticaria
Table 1
Characteristic of patients with chronic urticaria (
).
| | Variable | (%) |
| | Age (years), mean (SD) | 45.8 (13.5) | | Sex | | | Female | 54 (69.2) | | Male | 24 (30.8) | | Duration of disease (years) | | | ≤ 3 | 61 (78.2) | | >3 | 17 (21.8) | | Diamine oxidase (U/mL), median (IQR) | 5.40 (5.23) | | Response to second-generation antihistamines | | | Good response | 44 (57.9) | | Partial response | 30 (39.5) | | No response | 2 (2.6) | | Response to corticosteroid | | | Good response | 14 (70.0) | | Poor response | 6 (30.0) | | Response to montelukast | | | Good response | 6 (54.5) | | Poor response | 5 (45.5) | | Response to H2 blocker | | | Good response | 3 (37.5) | | Poor response | 5 (62.5) | | Response to low-histamine diet | | | Good response | 55 (76.4) | | Poor response | 17 (23.6) | | Contaminant angioedema | | | Presence | 13 (16.7) | | Absence | 65 (83.3) | | Predominant manifestation | | | Dermatographism | 14 (17.9) | | Chronic spontaneous urticaria | 64 (82.1) | | Long-lasting wheals | | | Presence | 9 (11.5) | | Absence | 69 (88.5) | | Erythrocyte sedimentation rate (mm/hour), median (IQR) | 7.00 (10.25) | | Eosinophil count (/μL), median (IQR) | 130.0 (96.5) | | IgE (IU/mL), median (IQR) | 103.0 (254.0) | | Antinuclear antibody | | | ≤ 1 : 40 | 66 (84.6) | | ≥ 1 : 80 | 12 (15.4) | | Hemoglobin (g/dL), mean (SD) () | 13.61 (1.61) | | Hematocrit (%), mean (SD) () | 41.0 (4.1) | | Specific food trigger | | | Presence | 43 (55.1) | | Absence | 35 (44.9) | | Exacerbation when NSAID use | | | Presence | 4 (5.1) | | Absence | 74 (94.9) |
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IQR: interquartile range; NSAID: nonsteroidal anti-inflammatory drug; SD: standard deviation.
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