A Substance P (SP)/Neurokinin-1 Receptor Axis Promotes Perineural Invasion of Pancreatic Cancer and Is Affected by lncRNA LOC389641

Figure 2

SP significantly increased the levels of NK-1R, NF-κB p65, and p-AKT expression. (a–d) The levels of NK-1R expression were assessed using the qRT-PCR, western blotting, and IF. (e) The levels of NF-κB p65 protein expression were evaluated using HDAC1 as a reference. (f) The levels of AKT and p-AKT proteins were evaluated using GAPDH as a reference. ns: no significant difference, , vs. SH-SY5Y-Vector group.

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