Methane Alleviates Lung Injury through the IL-10 Pathway by Increasing T Regulatory Cells in a Mouse Asthma Model

Figure 1

MS protects mice from OVA-induced lung injury as assessed by airway resistance and histology. Airway resistance measurements were performed by a FinePointe RC system supported by Huashan Hospital (Fudan University, Shanghai, China) (a); the histology shows 10x, 20x, and 40x magnification images of H&E staining of the lungs (b); the mucus score was assessed by cell infiltration: 0, no cells were observed; 1, a small amount of cells; 2, a ring of one cell deep; 3, a ring of 2-4 cells deep; and 4, a ring of more than four cells deep (c); eosinophil counts in peribronchial (d) and perivascular regions (e) of the lungs from three groups of mice were identified by the pink-stained cytoplasm. The data are presented in the form of the ( per group). and denote and , respectively, versus control group; # and ## denote and , respectively, versus asthma group.

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