Partial Reconstruction of Uterus Cervix in Rat by Decellularized Human Uterine Cervical Scaffold Combined with Adipose-Derived Stem Cells (ADSCs)

Figure 4

Surgical processes and gross examination of reconstruction of partial uterine cervical defect in rat. The schematic diagram of establishing mouse model of partial cervical injury (a). Surgical processes for two scaffold groups were shown: after exposure of uterine cervix (b), a tissue segment was excised from the cervix, then scaffold was implanted, respectively, with 6-0 sutures (c). The black arrow indicates the implantation site. Gross observation of rat uterus from the subtotal excision-only group (d), decellularized scaffold group (e), and recellularized scaffold group (f) was shown, respectively. Uterine patency test showed that the solution flowed freely out of the cervical end of the uterus, with the recellularized scaffold group as an example (g).

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