Research Article

LINC01094/SPI1/CCL7 Axis Promotes Macrophage Accumulation in Lung Adenocarcinoma and Tumor Cell Dissemination

Figure 7

LINC01094 binds to SPI1 to regulate CCL7 expression. (a) Correlation of LINC01094 with CCL7 predicted in the TCGA-LUAD database; (b) binding relationship between LINC01094 and SPI1 validated in TCGA-LUAD database; binding between LINC01094 and SPI1 examined by RIP (c) and biotin-LINC01094-based RNA pull down (d) assays; (e) subcellular localization of LINC01094 and SPI1 in H125 and A549 cells examined by FISH assay; mRNA (f) and protein (g) levels of CCL7 in A549 and H125 cells after LINC01094 knockdown examined by qPCR and WB analyses. . Data are presented as the . .
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