Exploring and Verifying the Mechanism and Targets of Shenqi Pill in the Treatment of Nonalcoholic Steatohepatitis via Network Pharmacology and Experiments
Table 2
Top 5 results of enrichment analysis of BP, CC, MF, and the pathways of SQP.
Ontology
ID
Description
GeneRatio
BgRatio
value
.adjust
value
BP
GO: 0032496
Response to lipopolysaccharide
6/8
330/18670
7.92-10
6.31-07
1.47-07
BP
GO: 0002237
Response to molecule of bacterial origin
6/8
343/18670
9.99-10
6.31-07
1.47-07
BP
GO: 0150076
Neuroinflammatory response
4/8
75/18670
1.66-08
6.99-06
1.63-06
BP
GO: 0010575
Positive regulation of vascular endothelial growth factor production
3/8
29/18670
1.88-07
5.54-05
1.29-05
BP
GO: 0002675
Positive regulation of acute inflammatory response
3/8
31/18670
2.31-07
5.54-05
1.29-05
MF
GO: 0005125
Cytokine activity
3/8
220/17697
1.01-04
0.006
0.002
MF
GO: 0005126
Cytokine receptor binding
3/8
286/17697
2.20-04
0.006
0.003
MF
GO: 0033613
Activating transcription factor binding
2/8
85/17697
6.27-04
0.012
0.005
MF
GO: 0048018
Receptor ligand activity
3/8
482/17697
0.001
0.015
0.006
MF
GO: 0070851
Growth factor receptor binding
2/8
134/17697
0.002
0.018
0.007
KEGG
hsa04657
IL-17 signaling pathway
5/8
94/8076
1.05-08
4.75-07
1.87-07
KEGG
hsa05163
Human cytomegalovirus infection
6/8
225/8076
1.17-08
4.75-07
1.87-07
KEGG
hsa04933
AGE-RAGE signaling pathway in diabetic complications
