Associations between Autoimmunity and Depression: Serum IL-6 and IL-17 Have Directly Impact on the HAMD Scores in Patients with First-Episode Depressive Disorder

Table 2

Comparisons in control group and FDD group before and after the treatment.

Index	Control group; ()	FDD group; ()		P value; t value
		Before treatment; ()	After treatment; ()	Control vs before	Control vs after	Before vs after
IL-6 (pg/mL)	16.84 ± 3.78	28.99 ± 5.51	18.69 ± 5.07	<0.001; t = −11.488	0.068; t = −1.850	<0.001; t = 11.083
IL-17 (pg/mL)	21.68 ± 3.72	41.15 ± 4.80	30.67 ± 3.47	<0.001; t = −20.278	<0.001; t = −11.177	<0.001; t = 12.272
CPR (mg/L)	2.83 ± 2.37	2.92 ± 2.51	3.58 ± 2.51	0.879; t = −0.153	0.175; t = −1.370	0.239; t = −1.186
HAMD scores	—	20.78 ± 3.10	6.73 ± 4.15	—	—	<0.001; t = 20.597

Note: IL, interleukin; FDD, first-episode depressive disorder; HAMD, Hamilton rating scale for depression; P < 0.01.