Identifying RBBP7 as a Promising Diagnostic Biomarker for BK Virus-Associated Nephropathy

Figure 4

Identification of the key module by WGCNA. (a) Analysis of the scale-free fit index (left) and the mean connectivity (right) for various soft-thresholding power values. (b) Clustering dendrogram of DEGs with assigned module colors. (c) Heat map of the correlation between modules and hallmark activities of BKVN. Each cell contains the Pearson correlation coefficient and value. (d) Histogram of the gene significance across modules for three hallmarks in BKVN. (e) Correlations of the expression levels of 19 genes that belong to grey60 module. Blue curves indicate negative correlations, and red curves indicate positive correlations.

(a)

(b)

(c)

(d)

(e)