Prognostic and Clinical Value of the Systemic Immune-Inflammation Index in Biliary Tract Cancer: A Meta-Analysis

Table 3

Correlations of SII and clinicopathological characteristics.

Clinicopathological features	No. of studies	No. of patients	Effects model	OR (95% CI)	value	Heterogeneity
						(%)	value
Lymph node metastasis (yes versus no)	5	1496	Random	1.44 (1.18-1.76)	<0.001	52.5	0.078
Vascular invasion (yes vs. no)	5	1431	Random	1.49 (1.05-2.13)	0.028	53.7	0.071
TNM stage (I–II vs. III-IV)	4	807	Random	1.52 (1.18-1.94)	0.001	75.2	0.007
Sex (male versus female)	7	1579	Fixed	0.96 (0.87-1.05)	0.384	0.0	0.925
Tumor differentiation (poor versus moderate/well)	5	1384	Fixed	1.06 (0.94-1.20)	0.492	79.1	0.001

CI: confidence interval; OR: odds ratio; SII: systemic immune-inflammation index; BTC: biliary tract cancer.