The Potential Diagnostic Value of Immune-Related Genes in Interstitial Fibrosis and Tubular Atrophy after Kidney Transplantation

Figure 3

Identification and evaluation of IF/TA diagnostic genes. (a and b) The LASSO regression with 10-fold cross-validation of LTF, FCGR2B, HLA-DQA2, EGF, ANGPTL3, and APOH. (c) The AUC of diagnostic model in the training set. (d) The AUC of diagnostic model in the validation set. (e) The AUCs of all 6 diagnostic genes in the GSE76882 dataset. (f) The AUCs of all 6 diagnostic genes in the GSE120495 dataset. (g and h) The expression patterns of 6 diagnostic genes from the GSE76882 and GSE120495 datasets. in the figure is a significance marker, stands for , stands for , stands for , and stands for . (i) Correlations between six key genes. The greater the correlation, the deeper the color (red is positive correlation and blue is negative correlation). (j) Protein interaction network of six genes.

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