miR-199a-5p Relieves Obstructive Sleep Apnea Syndrome-Related Hypertension by Targeting HIF-1α

Figure 4

Overexpressed miR-199a-5p attenuated vascular remodeling. (a) mRNA expression of miR-199a-5p in myocardial tissue by qRT-PCR. (b) Protein expression of HIF-1α, TGFβ1, and α-SMA in myocardial tissue by western blot and (c) quantification. (d) mRNA expression of miR-199a-5p in aortic tissue by qRT-PCR. (e) Protein expression of HIF-1α, TGFβ1, and α-SMA in aortic tissue by western blot and (f) quantification. CIH: chronic intermittent hypoxia; NC: negative control. , compared with control; ^#, ^##, and ^### compared with CIH+NC.

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