Effect of Perioperative Interleukin-6 and Tumor Necrosis Factor-α on Long-Term Outcomes in Locally Advanced Gastric Cancer: Results from the CLASS-01 Trial
Table 1
Baseline characteristics of patients with gastric cancer.
Characteristics
%
Age (years, )
Gender
Female
51
38
Male
84
62
ECOG score
0
97
72
1
36
27
Missing
2
1
BMI (kg/m2, WHO)
< 25
133
84
≥ 25
22
16
Clinical TNM stage
I
6
4
II
59
44
III
70
52
Types of surgery
Laparoscopic gastrectomy
67
50
Open gastrectomy
68
50
Pathological TNM stage
I
44
33
II
46
34
III
45
33
Complication
Yes
29
22
No
106
79
Chemotherapy
Yes
65
48
No
70
52
White blood cell (109/L, median, IQR)
5.89 (4.90-7.02)
Neutrophil (109/L, median, IQR)
3.34 (2.64-4.17)
Lymphocyte (109/L, median, IQR)
1.90 (1.61-2.22)
C-reactive protein (mg/L, median, IQR)
0.9 (0.3-2.1)
IL6_0 (pg/mL, median, IQR)a
5.95 (2.50-14.8)
IL6_1 (pg/mL, median, IQR)a
70.90 (40.28-130.28)
IL6_3 (pg/mL, median, IQR)a
39.65 (17.83-75.10)
IL6_5 (pg/mL, median, IQR)a
18.50 (10.50-43.10)
TNFα_0 (pg/mL, median, IQR)a
11.40 (8.35-19.45)
TNFα_1 (pg/mL, median, IQR)a
12.10 (9.20-21.10)
TNFα_3 (pg/mL, median, IQR)a
16.50 (13.00-24.00)
TNFα_5 (pg/mL, median, IQR)a
15.00 (11.00-13.00)
The IL6_0 was tested preoperatively, and the factors of IL6_1, IL6_3, and IL6_5 were tested on first, third, and fifth days after operation, separately. The TNFα_0 was tested preoperatively, and the factors of TNFα_1, TNFα_3, and TNFα_5 were tested on first, third, and fifth days after operation, separately.
