Identification of Hub Genes Involved in Tubulointerstitial Injury in Diabetic Nephropathy by Bioinformatics Analysis and Experiment Verification

Figure 3

Identification and enrichment analyses of DEGs related to tubulointerstitial injury in DN. (a) Volcano plot of differential expressed genes (DEGs) between DN and LD tubule samples. The -axis corresponds to log₂ transformed fold change, and the -axis corresponds to –log₁₀ transformed value. (b) Heat map of DEGs among 2 groups. (c, d) GO and KEGG pathway enrichment results for DEGs. (e) GSEA between the DN and LD groups. DEG: differentially expressed gene; GSEA: gene set enrichment analysis.

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