Identification of Hub Genes Involved in Tubulointerstitial Injury in Diabetic Nephropathy by Bioinformatics Analysis and Experiment Verification

Figure 4

PPI network analysis and key genes’ recognition. (a) PPI network for DEGs. Red rectangle node: upregulated genes; green rectangle node: downregulated genes. (b) Key genes were screened using Cytoscape cytoHubba plugin based on the four methods, Degree, Betweenness, Closeness, and MNC. PPI: protein–protein interaction.

(a)

(b)