Identification of Hub Genes Involved in Tubulointerstitial Injury in Diabetic Nephropathy by Bioinformatics Analysis and Experiment Verification

Figure 5

Screening and validation of key genes. (a) 11 key genes were selected from the intersected top 20 genes in the above four screening methods. Validation of expression levels of hub genes from the GSE30529 dataset. 11 key genes showed the similar upregulation trend: (b) ALB, (c) TIMP1, (d) C3, (e) EGF, (f) CCL2, (g) VCAM1, (h) CLU, (i) PLG, (j) ANXA2, (k) FOS, and (l) ANXA1.

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