The BRD4 Inhibitor dBET57 Exerts Anticancer Effects by Targeting Superenhancer-Related Genes in Neuroblastoma

<div>sh-TBX3 exhibits tumor growth inhibition effect in xenograft tumor model. (a) Flow chart of the xenograft tumor model. (b) Tumor signal values in nude mice. (c) Measurement of tumor size in control and experimental groups. (d) Statistics of the average weight of the two groups of tumors. (e) Tumor growth curves of experimental group and control group. (f–h) Immunohistochemistry of TBX3, Ki67, and Caspase3. Scale bars: 100 <i>μ</i>m. 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Journal of Immunology Research

fig8

Figure 8

Figure 8: The BRD4 Inhibitor dBET57 Exerts Anticancer Effects by Targeting Superenhancer-Related Genes in Neuroblastoma 