Th22 Cells/IL-22 Serves as a Protumor Regulator to Drive Poor Prognosis through the JAK-STAT3/MAPK/AKT Signaling Pathway in Non-Small-Cell Lung Cancer

<div>The level of Th22 cells in PBMCs is positively correlated with the pathological stage, lymph node metastasis, and clinical tumor biomarkers in lung cancer. (a) The relationship between Th22 cells in PBMCs and TNM stage (version 8) is shown. (b) The relationship between Th22 cells in PBMCs and metastasis is shown. The degree of lymph node metastasis was determined according to the 8th TNM classification. (c) The correlation between Th22 cells and serum CEA in adenocarcinoma (AC) patients. (d) The correlation between Th22 cells and serum CYFRA21-1 in squamous cell carcinoma (SCC) patients. 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Journal of Immunology Research

fig2

Figure 2

Figure 2: Th22 Cells/IL-22 Serves as a Protumor Regulator to Drive Poor Prognosis through the JAK-STAT3/MAPK/AKT Signaling Pathway in Non-Small-Cell Lung Cancer 

Figure 2 | Th22 Cells/IL-22 Serves as a Protumor Regulator to Drive Poor Prognosis through the JAK-STAT3/MAPK/AKT Signaling Pathway in Non-Small-Cell Lung Cancer 