Th22 Cells/IL-22 Serves as a Protumor Regulator to Drive Poor Prognosis through the JAK-STAT3/MAPK/AKT Signaling Pathway in Non-Small-Cell Lung Cancer

Figure 3

IL-22 promoted the cell migration of lung cancer cells. PC-9 and A549 cells were treated with IL-22 (0, 5, 10, 50, and 100 ng/mL) for 48 hours. The effect of IL-22 on tumor cell migration was evaluated by wound healing assay (scale  μm) (a) and Transwell assay (scale  μm) (b). The data are representatives of three independent experiments and presented as (SD). , , and , compared to the low concentration group.

(a)

(b)