Suppression of T-Cell Proliferation by Normal Density Granulocytes Led to CD183 Downregulation and Cytokine Inhibition in T-Cells

Figure 5

NDGs suppress cytokine production of Th cells in a dose-dependent manner. T-cells (100 000/well) were cocultured with different amounts of NDGs (5000, 10 000, 20 000, 30 000, 40 000, or 50 000/well). After 3 days of coculture, the supernatant was saved and used in a CBA to measure the presence of (a) IL-2, (b) IL-4, (c) IL-6, (d) IL-10, (e) TNF, (f) IFN-g, and (f) IL-17A. Graphs show median with 95% CI ().

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