lncRNA MALAT1 Promotes Diabetic Nephropathy Progression via miR-15b-5p/TLR4 Signaling Axis

Figure 2

Knockdown of MALAT1 attenuates HG-induced cell viability inhibition, apoptosis, and expression of inflammatory cytokines in HK-2 cells. (a) qRT-PCR analysis of MALAT1 in HK-2 cells after transfection with si-MALAT1 or si-NC. versus the HG or si-NC group. (b) Cell viability by CCK-8 assay. versus the HG or si-NC group. (c, d) Cell apoptosis by TUNEL assay. versus the HG or si-NC group. (e–g) ELISA analysis of TNF-α, IL-1β, and IL-6. versus the HG or si-NC group.

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