Research Article
lncRNA MALAT1 Promotes Diabetic Nephropathy Progression via miR-15b-5p/TLR4 Signaling Axis
Table 1
Clinical characteristics of DN patients.
| | Case number | Sex (M/F) | Age (years) | BMI (kg/m2) | SBP (mmHg) | DBP (mmHg) | Hb (g/L) | Scr (umol/L) | ALB (g/L) | TC (mmol/L) | Proteinuria (g/d) | HbA1c (%) | Duration of DM (years) | Retinopathy (yes/no) |
| | 1 | M | 41 | 22.1 | 120 | 80 | 92 | 112 | 31.9 | 3.56 | 6.17 | 6.84 | 4 | Yes | | 2 | F | 53 | 23.4 | 125 | 85 | 111 | 106 | 33.4 | 6.92 | 5.29 | 7.04 | 6 | Yes | | 3 | F | 53 | 22.3 | 169 | 90 | 87 | 69 | 42 | 3.49 | 3.77 | 10.05 | 6 | Yes | | 4 | M | 51 | 22.6 | 179 | 101 | 107 | 103 | 44.5 | 2.82 | 1.03 | 6.5 | 5 | Yes | | 5 | F | 41 | 26.7 | 169 | 88 | 74 | 151 | 26.2 | 6.05 | 5.23 | 8.3 | 7 | No | | 6 | F | 51 | 23.6 | 107 | 65 | 121 | 106 | 43.9 | 4.05 | 0.51 | 4.43 | 5 | No | | 7 | M | 50 | 24.8 | 148 | 108 | 128 | 105 | 26.8 | 6.32 | 6.2 | 10.1 | 4 | Yes | | 8 | M | 46 | 27.5 | 153 | 97 | 110 | 167 | 23.5 | 7.3 | 10.12 | 5.6 | 7 | Yes | | 9 | F | 53 | 25.4 | 130 | 92 | 127 | 126 | 39.8 | 6.98 | 2.81 | 6.1 | 8 | No | | 10 | F | 47 | 23.5 | 122 | 84 | 96 | 77 | 30.1 | 4.59 | 5.93 | 4.87 | 4 | Yes | | 11 | M | 42 | 28.9 | 219 | 137 | 123 | 119 | 25.8 | 4.48 | 7.59 | 5.4 | 5 | Yes | | 12 | F | 45 | 22.8 | 134 | 99 | 86 | 88 | 29 | 6.03 | 4.19 | 5.8 | 6 | Yes | | 13 | F | 65 | 27.4 | 146 | 86 | 101 | 212 | 19.5 | 12.53 | 11.23 | 6.1 | 8 | Yes | | 14 | F | 48 | 24.6 | 130 | 80 | 97 | 74 | 35.3 | 5.2 | 2.46 | 11.9 | 6 | No | | 15 | F | 56 | 27.4 | 145 | 73 | 118.8 | 86 | 40.8 | 9.06 | 2.3 | 9.74 | 5 | Yes | | 16 | F | 52 | 25.2 | 120 | 80 | 97 | 130 | 38.4 | 4.15 | 4.17 | 7.74 | 7 | No | | 17 | F | 50 | 22.7 | 110 | 70 | 104.4 | 67.1 | 40 | 4.09 | 0.53 | 9.45 | 5 | Yes | | 18 | M | 45 | 23.2 | 142 | 90 | 78.3 | 259 | 36.2 | 2.58 | 4.995 | 5.7 | 6 | Yes |
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Abbreviations: BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; Hb: hemoglobin; Scr: serum creatinine; TC: total cholesterol; ALB: serum albumin.
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