Association of HLA-DR1, HLA-DR13, and HLA-DR16 Polymorphisms with Systemic Lupus Erythematosus: A Meta-Analysis

Table 1

Characteristics of included studies in this meta-analysis.

Study	Year	Country/area	Ethnicity	Matching criteria	Sample size		Mean age		Diagnostic criteria	Detection methods
					SLE	Control	SLE	Control
Fojtíková et al. [15]	2011	Czech Republic	Caucasian	Age	123	99	43.4	39.3	ACR	PCR-SSP
Furukawa et al. [16]	2014	Japan	East Asian	Age	848	849	45.2	36.0	ACR	PCR-SSOP
Garcia-Silva et al. [17]	2021	Mexico	North American	Ethnicity	40	99	30	NA	ACR	PCR-SSP
Goldstein and Sengar [18]	1993	Canada	North American	NA	91	89	NA	NA	ACR	RFLP
Hachicha et al. [19]	2018	Tunisia	African	Age	75	123	32	32	ACR	PCR-SSP
Hrycek et al. [20]	2005	Poland	Caucasian	Age	24	36	41	36	ACR	PCR-SSP
Katkam et al. [21]	2018	India	South Asian		212	227	28.04	30.00	ACR	PCR-SSP
Kim et al. [22]	1996	Korea	East Asian	Ethnicity	97	281	NA	NA	ACR	PCR-SSP
Lu et al. [23]	1997	Taiwan	East Asian	Ethnicity	105	115	29.2	NA	ACR	PCR-SSP
Mohd-Yusuf et al. [24]	2011	Malaysia	East Asian	NA	160	107	NA	NA	ACR	PCR-SSP
Naves et al. [25]	1998	Spain	Caucasian		46	47	NA	NA	ACR	PCR-SSOP
Reveille et al. [26]	1998	USA	North American	NA	225	393	35.6	NA	ACR	PCR-SSOP
Rood et al. [27]	2000	Netherlands	Caucasian	Ethnicity	99	177	NA	NA	ACR	PCR-SSOP
Selvaraja et al. [28]	2021	Malaysia	East Asian	NA	100	951	30.6	NA	ACR	PCR-SSOP
Vasconcelos et al. [29]	2009	Portugal	Caucasian	Ethnicity	213	223	NA	NA	ACR	PCR-SSP
Wadi et al. [30]	2014	Saudi Arabia	South Asian	NA	51	30	NA	NA	ACR	PCR-SSP
Yao et al. [31]	1993	Germany	Caucasian	NA	178	207	NA	NA	ACR	PCR-SSOP
Zhang et al. [32]	1997	China	East Asian	NA	51	106	NA	NA	ACR	PCR-SSP

ACR: American College of Rheumatology Criteria; PCR: polymerase chain reaction; SSP: sequence-specific primers; SSOP: sequence-specific oligonucleotide probe; RFLP: restriction fragment length polymorphism; NA: not available.