Different In Situ Immune Patterns between Primary Tumor and Lymph Node in Non-Small-Cell Lung Cancer: Potential Impact on Neoadjuvant Immunotherapy

Figure 3

The densities of stromal PD-L1-positive T cells (S-PD-L1+CD3+) in the center of tumor (CT) region (a) were significantly correlated between primary tumor (PT) and metastatic lymph node (mLN); (b) in contrast, a marginally significant correlation was found in the invasive margin (IM) region. The densities and frequencies of S-PD-L1+CD3+ were significantly higher in mLNs than in PTs irrespective of location. CT = center of tumor; IM = invasive margin; S = stroma ; .

(a)

(b)