Research Article

Is Vitamin D Deficiency the Cause or the Effect of Systemic Lupus Erythematosus: Evidence from Bidirectional Mendelian Randomization Analysis

Figure 2

MR results for causal role of systemic lupus erythematosus on serum vitamin D and 25-hydroxyvitamin D levels. MR-RAPS method was not applicable for causal effect from SLE on vitamin D with model 2 for limited SNPs. SLE: systemic lupus erythematosus; SNP: single-nucleotide polymorphisms; IVW: inverse variance weighted; MR-RAPS: MR-robust adjusted profile score.