HBV Infection-Related PDZK1 Plays an Oncogenic Role by Regulating the PI3K-Akt Pathway and Fatty Acid Metabolism and Enhances Immunosuppression

Figure 2

PDZK1 is one of the HBV-infection-related oncogenes in human HCC. (a) Venny map indicating the common up- or downregulated genes both in cancer and normal samples from TCGA-LIHC. (b) Heat map reflating either or value obtained from multiple correlation study between HBV reads and gene expression level of common genes. (c) Scatter plot reflecting the correlation between HBV reads and PDZK1 expression in the TCGA samples. (d) The comparison of PDZK1 expression between normal and tumor samples from TCGA-LIHC or TCGA-LIHC and GTEx database. (e) Real-time PCR detection PDZK1 transcription in the sample sets indicated in the figure. (f) Scatter plot reflecting the correlation between HBV reads and PDZK1 expression from clinical samples.

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