Research Article

HBV Infection-Related PDZK1 Plays an Oncogenic Role by Regulating the PI3K-Akt Pathway and Fatty Acid Metabolism and Enhances Immunosuppression

Figure 4

PDZK1 was correlated to increased PI3K/AKT and fatty acid metabolism. (a) Real-time PCR detection PI3K-AKT signaling-related genes indicated in the figure in PDZK1 high and low expression samples. (b) IHC staining of ITGA6, RAF1, and FGFR3 in PDZK1 high and low expression samples. (c, d) Real-time PCR detection fatty acid metabolism and degradation-related genes indicated in the figure in PDZK1 high and low expression samples. (e) IHC staining of ADH5 and FASN in PDZK1 high and low expression samples. Data are presented as and were analyzed using Student’s -test (, ; ns: not significant, ).
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