HBV Infection-Related <i>PDZK1</i> Plays an Oncogenic Role by Regulating the PI3K-Akt Pathway and Fatty Acid Metabolism and Enhances Immunosuppression

<div>Expression of PDZK1 in HCC tissues was associated with Treg, and tumor-associated macrophages (TAMs) induced immunosuppression. (a) ssGSEA analysis for PDZK1 top 20 high and low expression TCGA samples by using previously reported gene sets. (b) GSEA analysis for PDZK1 top 20 high and low expression TCGA samples. (c) IHC and multiple color IHC staining for CD68, CD163, and CD4/FOXP3 in PDZK1 high and low expression samples. 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Journal of Immunology Research

fig5

Figure 5

Figure 5: HBV Infection-Related <i>PDZK1</i> Plays an Oncogenic Role by Regulating the PI3K-Akt Pathway and Fatty Acid Metabolism and Enhances Immunosuppression 

Figure 5 | HBV Infection-Related PDZK1 Plays an Oncogenic Role by Regulating the PI3K-Akt Pathway and Fatty Acid Metabolism and Enhances Immunosuppression 