Concurrent Chemoradiotherapy Increases the Levels of Soluble Immune Checkpoint Proteins in Patients with Locally Advanced Cervical Cancer

Figure 2

Significant changes in the sICPs after CCRT. The serum levels of BTLA, CD40, GITRL, PD-1, CTLA-4, CD80, CD86, PD-L1, and ICOS were compared among pre-CCRT (green), mid-CCRT (blue), and post-CCRT (red), showing significant changes after CCRT. values were calculated using the Friedman test with Bonferroni’s post-test.