Role of Autophagy Inducers and Inhibitors in Intestinal Barrier Injury Induced by Intestinal Ischemia–Reperfusion (I/R)

Figure 5

The effects of 3-MA and RAP on the epithelial barrier after intestinal IRI. (a) The change in intestinal permeability was detected by the concentrations of serum FITC-dextran. (b) The relative level of claudin-2 mRNA was measured by RT–qPCR. (c) The protein expression levels of occludin and claudin-2. (d) Representative images of occludin/claudin-2 coimmunofluorescence staining in the intestine after IRI. , , , and vs. the sham group; ^##, ^#### vs. the I/R group. per group in the sham and I/R groups, and per group in the other groups.

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