Multiple CD59 Polymorphisms in Chinese Patients with Mycobacterium tuberculosis Infection

Table 4

The relevance between single nucleotide polymorphisms and susceptibility to tuberculosis.

SNP	Test	Comparison	Cases	Controls	OR(95% CI)	χ^2	P-value
rs1047581	Genotypes	CT/TT	138/756	240/1,278	0.97(0.77, 1.22)	0.004	0.807
(n = 2428)		CC/TT	5/756	11/1,278	0.77(0.27, 2.22)	0.056	0.627
	Alleles	C/T	148/1,650	262/2,796	0.96(0.78, 1.18)	0.166	0.684
	DOM	(CC + CT)/TT	143/756	251/1,278	0.96(0.77, 1.21)	0.108	0.742
	REC	(CT + TT)/CC	894/5	1518/11	1.29(0.45, 3.74)	0.231	0.631
rs7046	Genotypes	AG/GG	433/279	754/475	0.98(0.81, 1.18)	0.055	0.815
(n = 2430)		AA/GG	186/279	303/475	1.05(0.83, 1.32)	0.135	0.713
	Alleles	A/G	805/991	1,360/1,704	1.02(0.91, 1.14)	0.087	0.768
	DOM	(AG + AA)/GG	619/279	1,057/475	1.00(0.83, 1.19)	0.001	0.974
	REC	(AG + GG)/AA	712/186	1,229/303	0.94(0.77, 1.16)	0.308	0.579
rs2231460	Genotypes	AG/GG	0/900	3/1,529	0.24(0.01, 4.70)	0.876	0.349
(n = 2432)		AA/GG	0/900	0/1,529	1.70(0.03, 85.68)	0.070	0.791
	Alleles	A/G	0/1,800	3/3,061	0.24(0.01, 4.71)	1.763	0.184
	DOM	(AG + AA)/GG	0/900	3/1,529	0.24(0.01, 4.70)	0.876	0.349
	REC	(AG + GG)/AA	900/0	1,532/0	1.70(0.03, 85.85)	0.071	0.791
rs184251026	Genotypes	TG/GG	11/889	13/1,516	1.44(0.64, 3.23)	0.794	0.373
(n = 2329)		TT/GG	0/889	0/1,516	1.70(0.03, 86.00)	0.071	0.789
	Alleles	T/G	11/1,789	13/3,045	1.44(0.64, 3.22)	0.797	0.372
	DOM	(TT + TG)/GG	11/889	13/1,516	1.44(0.64, 3.24)	0.890	0.365
	REC	(GG + TG)/TT	900/0	1,529/0	1.70(0.03, 85.68)	0.070	0.791
rs41275164	Genotypes	AG/GG	1/899	2/1,531	0.86(0.08, 9.51)	0.015	0.903
(n = 2433)		AA/GG	0/899	0/1,531	1.72(0.03, 86.85)	0.074	0.786
	Alleles	A/G	1/1,799	2/3,064	0.85(0.08, 9.40)	0.017	0.896
	DOM	(AG + AA)/GG	1/899	2/1,531	0.85(0.08, 9.40)	0.017	0.896
	REC	(AG + GG)/AA	900/0	1,533/0	1.70(0.03, 85.90)	0.071	0.791
rs831633	Genotypes	AG/GG	434/247	743/437	1.03(0.85, 1.26)	0.108	0.742
(n = 2429)		AA/GG	218/247	350/437	1.10(0.88, 1.39)	0.684	0.408
	Alleles	A/G	870/928	1,443/1617	1.05(0.93, 1.18)	0.687	0.407
	DOM	(AG + AA)/GG	652/247	1,093/437	1.06(0.88, 1.27)	0.331	0.565
	REC	(AG + GG)/AA	681/218	1,180/350	0.92(0.76, 1.12)	0.596	0.440
rs704700	Genotypes	GA/AA	351/500	545/897	1.16(0.97, 1.37)	2.676	0.102
(n = 2429)		GG/AA	46/500	90/897	0.92(0.63, 1.33)	0.209	0.648
	Alleles	G/A	443/1,351	725/2,339	1.06(0.92, 1.21)	0.659	0.417
	DOM	(AG + GG)/AA	397/500	635/897	1.12(0.95, 1.33)	1.828	0.176
	REC	(AG + AA)/GG	851/46	1,442/90	1.15(0.80, 1.66)	0.596	0.440
rs41275166	Genotypes	GA/AA	1/899	2/1,522	0.85(0.08, 9.35)	0.018	0.892
(n = 2427)		GG/AA	0/899	3/1,522	0.24(0.01, 4.69)	0.882	0.348
	Alleles	G/A	1/1,799	8/3,046	0.21(0.03, 1.69)	2.140	0.143
	DOM	(AG + GG)/AA	1/899	5/1,522	0.34(0.04, 2.90)	0.976	0.323
	REC	(AG + AA)/GG	900/0	1,524/3	4.13(0.21, 80.14)	0.882	0.348
rs10768024	Genotypes	CT/TT	287/580	490/959	0.97(0.81, 1.16)	0.124	0.725
(n = 2430)		CC/TT	30/580	84/959	0.59(0.38, 0.91)	5.779	0.016
	Alleles	C/T	347/1,447	658/2,408	0.88(0.76, 1.02)	3.098	0.078
	DOM	(CT + CC)/TT	317/580	574/959	0.91(0.77, 1.08)	1.078	0.299
	REC	(CT + TT)/CC	867/30	1,449/84	1.68(1.10, 2.56)	5.769	0.016

Note: SNP, single nucleotide polymorphisms; DOM, dominant model; REC, recessive model. Individuals with missing data were excluded.