Activation of Most Toll-Like Receptors in Whole Human Blood Attenuates Platelet Deposition on Collagen under Flow

Figure 3

Pam3CSK4 dose dependently inhibit platelet deposition onto collagen under flow. PPACK WB treated with HBS (control) or different concentrations of Pam3CSK4 was perfused over collagen at 100 s^-1 for 720 seconds. CD61 was added to all channels to label for platelets. Platelet FI was measured throughout the course of the experiments (a) and Figure 3(b) shows how they looked under the microscope.

(a)

(b)