miR-1 Inhibits the Ferroptosis of Chondrocyte by Targeting CX43 and Alleviates Osteoarthritis Progression

Figure 3

CX43 was the target of miR-1. (a) Venn diagram showing the potential target mRNAs of miR-1, as identified by four different independent microRNA-target-predicting online databases (Target scan, miRDB, PicTar, and miRTarBase). (b) The predicted sequence in the 3′-UTR of CX43 targeted by miR-1. (c) Luciferase reporter assay used to confirm that CX43 is the target of miR-1. (d) Western blot analysis of the expression level of CX43 in chondrocytes transfected with Agomir-1 or Antagomir-1. Data were presented as the mean ± SD of at least three replicates. ; ns, no statistical significance.

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