Exosome Derived from Human Umbilical Cord Mesenchymal Cell Exerts Immunomodulatory Effects on B Cells from SLE Patients

Figure 7

Schematic representation of immunomodulatory effects of hucMSCs-Exo on B cells from SLE patients. By coculture hucMSCs-Exo with B cells of SLE patients, B cells apoptosis can be promoted, B-cells proliferation can be inhibited, overactivation of B-cells can be prevented, inflammation can be alleviated, and disease progression can be slowed by reducing miR-155 targeting SHIP-1 in B cells.