Pollen Food Allergy Syndrome in Japanese Children and Adolescents: Risk Factors and Pollen Sensitisation
Table 1
Clinical characteristics of the participants.
Total
Age, in years
value 1 (for all group)
value 2
3–6 (G1)
7–12 (G2)
13–18 (G3)
G1 vs. 2
G1 vs. 3
G2 vs. 3
600
199
244
157
Sex (male : female)
378 : 222
124 : 75
158 : 86
96 : 61
0.743
—
—
—
Age (median : min–max)
9 : 3-18
Allergic diagnosis
Food allergy†
365 (60.8%)
141 (70.9%)
149 (61.1%)
75 (47.8%)
<0.001
0.035
<0.001
0.023
Atopic dermatitis
288 (48.0%)
105 (52.8%)
113 (46.3%)
70 (44.6%)
0.244
—
—
—
Bronchial asthma
200 (33.3%)
57 (28.6%)
90 (36.9%)
53 (33.8%)
0.186
—
—
—
Seasonal allergic rhinitis
462 (77.0%)
110 (55.2%)
210 (86.1%)
142 (90.4%)
<0.001
<0.001
<0.001
0.522
PFAS
123 (20.5%)
17 (8.5%)
49 (20.0%)
57 (36.3%)
<0.001
<0.001
<0.001
<0.001
Sex (male : female)
75 : 48
13 : 4
28 : 21
34 : 23
0.602
0.296 (G1)‡
0.243 (G2)‡
0.865 (G3)‡
Pollen-specific IgE-positive rate
Alder
371 (61.8%)
95 (47.7%)
165 (67.6%)
111 (70.7%)
<0.001
<0.001
<0.001
0.581
Japanese cedar
594 (99.0%)
195 (98.0%)
244 (100%)
155 (98.7%)
0.099
—
—
—
Ragweed
338 (56.3%)
87 (43.7%)
150 (61.4%)
101 (64.3%)
<0.001
<0.001
<0.001
0.598
Orchard grass
380 (63.3%)
91 (45.7%)
167 (68.4%)
122 (77.7%)
<0.001
<0.001
<0.001
0.052
†Excluding PFAS. value 1: Fisher’s exact test. value 2: pairwise comparison (Fisher’s exact test with Bonferroni correction), ‡ value 2: comparison within age groups for gender (Fisher’s exact test).
